Vijay Sethupathi

Dr. Dharmadurai

Tamannaah Bhatia

Dr. Subhashini

Srushti Dange

Dr. Stella

Aishwarya Rajesh

Anbuselvi

Radikaa Sarathkumar

Pandiyamma

Aruldoss

Beemaraasu

M. S. Bhaskar

Paraman

Rajesh

Principal Dr. Kamaraj

Soundara Raja

Archunan

Ganja Karuppu

Compounder Gopal

R. K. Suresh

Cameo Appearance in "Makka" song.

Madhuvanti Arun

Police Officer

Florent Pereira

Saravana Sakthi

Abi Nakshathra

Vishalini Daniel