María Callas

Medea

Massimo Girotti

Creonte

Laurent Terzieff

Chirone

Giuseppe Gentile

Giasone

Margareth Clémenti

Glauce

Paul Jabara

Pelias

Sergio Tramonti

Apsirto, Medea's Brother

Annamaria Chio

Wet Nurse

Piera Degli Esposti

Woman

Mirella Pamphili

Rossana Canghiari

Servant of Glauce (uncredited)

Maria Cumani Quasimodo

(uncredited)

Rita Savagnone

Voice Dubbing: Maria Callas / Medea (voice) (uncredited)

Pino Colizzi

Voice Dubbing: Giuseppe Gentile / Jason (voice) (uncredited)

Enrico Maria Salerno

Voice Dubbing: Laurent Terzieff / Centaur (voice) (uncredited)